Inflammation - Pain

Description | Research Themes | Researchers

Urogynecology Research Laboratory led by Melanie Morin, Ph.D.Studying phenomena related to inflammation and pain is this axis main objective. Its researchers are investigating the inflammatory processes involved in inflammatory bowel and joint diseases, autoimmune diabetes, aging, cystic fibrosis, asthma, neurodegeneration, and neuroinflammation in order to shed light on the mechanisms involved in these phenomena.

Several other researchers are working on the development and characterization of new molecules for the treatment of pain, the analysis of brain responses, and the role of sex hormones in pain as well as studies on pain physiopathology, neurophysiology, and chronification.

Axis research also involves intestinal flora as well as the interactions between a host and its pathogens, such as influenza and prions.

The various types of research work are carried out from the basic-science and clinical approaches on different pathologies ranging from asthma and cystic fibrosis to rheumatoid arthritis, including Crohn's disease and gynecological pain.
Axis Director | Louis Gendron, Ph. D.

Axis Coordinator | Karine Tremblay

    Research Themes

    • Inflammatory bowel and joint diseases: Study of the mechanisms involved in Crohn's disease, chronic intestinal inflammation, and colorectal cancer

    • Acute and chronic pain: Study of the mechanisms involved in pain perception and transmission. Development and characterization of molecules that attenuate or inhibit pain. Study of the quality of life of chronic-pain patients

    • Neurodegeneration and neuroinflammation: Study of neural pathologies such as Alzheimer's disease and multiple sclerosis

    • Asthma and cystic fibrosis: Study of the mechanisms involved in allergies and pulmonary inflammatory diseases, including asthma and cystic fibrosis

    • Infectious diseases (e.g., influenza, prions, and intestinal microflora): Study of the interactions between pathogens and their hosts as well as the inflammatory responses induced by these interactions

    • Diabetes and autoimmune diseases: Study of the mechanisms involved in the development of autoimmune diseases such as diabetes, Alzheimer's disease, Graves' disease, Paget's disease, Addison's disease, and rheumatoid arthritis


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